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HHC Cannabinoide Marijuana

HHC: Properties and Effects of an Illegal Cannabinoid!

HHC: Properties and Effects of the New Illegal Cannabinoid in Italy!

Welcome everyone to this new chapter of our blog about the incredible medical properties of the Cannabinoid HHC, the Cannabinoid that has recently become illegal in Italy! After seeing the History, Taste and Effects of Animal Mints, follow us on this new article by Hannibal Seedsshop about HHC, the twin cannabinoid of THC!


In the context of research on cannabinoids, the active ingredients produced by female Marijuana plants, one substance that has attracted the attention of experts and the public is “Hexahydrocannabinol”. This molecule has aroused considerable interest due to its potential properties and therapeutic applications.

This article will explore the origin of this incredible cannabinoid, its continued popularity, the effects it is thought to have, and the current legal status.

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Origins of the Cannabinoid HHC

HHC was first synthesized in the laboratory of Professor Raphael Mechoulam at the Hebrew University of Jerusalem in the 1970s. Mechoulam is a leading figure in cannabinoid research and was the first to isolate delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) from the cannabis plant.

While studying him, Mechoulam discovered that HHC was a metabolite of THC that is formed during the long-term storage of cannabis. This discovery has sparked interest in the potential properties of HHC and its effects on the human body.

Continued popularity of the HHC

Despite being discovered several decades ago, its popularity has steadily grown over the years. This is partly due to the growing attention towards cannabinoids and their possible therapeutic benefits.

Preliminary studies suggest that HHC may have similar effects to other cannabinoids, such as THC and CBD, but with a different chemical composition which could lead to different reactions in the body. This has piqued the curiosity of scientists and consumers interested in alternatives to traditional treatments.

Effects and Applications

The effects of HHC are not yet fully understood, as research is still ongoing. However, this natural substance is thought to affect the endocannabinoid system, which is involved in regulating a number of physiological functions.

Some scholars speculate that HHC may have potential effects on pain relief, anxiety, insomnia, and other conditions similar to those treated with better-known cannabinoids like THC and CBD.

It is important to underline that scientific research is still in a preliminary stage and that further studies are needed to fully understand its effects and potential therapeutic applications. Therefore, it is advisable to consult a medical professional before using any product containing HHC to address health concerns.

5 Main Differences Between HHC vs THC

  • Chemical Structure: The main difference between HHC vs THC lies in their chemical structure. While both are cannabinoids, HHC has a slightly different structure than THC. This difference in structure can affect the reactivity of the compound in the human body.
  • Psychoactive Effects: THC is known to be primarily responsible for the psychoactive effects associated with cannabis. It generates feelings of euphoria, alterations of perception and can cause mental “swirls”. On the other hand, research on this new cannabinoid suggests that it may have less intense psychoactive effects than THC. This makes HHC a compound of interest to those seeking the therapeutic benefits of cannabinoids without the intense mental alteration associated with the highly sought-after THC.
  • Activity in the Endocannabinoid System: Both act on the endocannabinoid system, but differences in their chemical structure can lead to different interactions with cannabinoid receptors in the human body. These interactions can affect pain perception, mood, and other physiological functions.
  • Therapeutic Potential: THC has been extensively studied for its potential therapeutic benefits, such as the management of chronic pain and chemotherapy-induced nausea. As for HHC, research is still ongoing to clearly establish its therapeutic effects. However, some sources indicate that it may have similar properties to THC but with a potentially milder side effect profile.
  • Legislation: The legality of HHC can vary by jurisdiction, but in many places, its legal status is related to cannabis laws. Since it is a substance that is extracted and synthesized from cannabis, its legality could be affected by the laws that regulate this plant.

Legal Status of the HHC Cannabinoid

The legal status of the HHC varies from country to country and, in some cases, from state to state. Since it is a derivative of cannabis, its legality is often linked to the cannabis laws in the jurisdiction where it is located. In many jurisdictions, cannabis and its derivatives are still considered controlled substances, which could also affect the legality of this substance.

As the legal situation with cannabinoids is constantly evolving, it is vital to be aware of local laws before purchasing or using products containing HHC. In some places, this important active ingredient in Marijuana may be legally accessible for research purposes, while in others it may be considered illegal or severely restricted.

HHC Illegal in Italy since 2023

In Italy, where Annibale Seedsshop resides, this cannabinoid became illegal during 2023 as the effect this substance can have on the body and psyche is still doubtful. For this reason, since 28 July 2023 the trade of this cannabinoid in Italy has been illegal like THC.

Here on Annibale Seedsshop you won’t find herbs with a high HHC content, but only fully legal cannabinoids such as CBD, CBG and CBN!

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The cannabinoid HHC is a molecule that has captured the interest of researchers and the public interested in cannabinoids and their possible therapeutic applications. Its origins date back to the laboratory of Professor Raphael Mechoulam, and it has since gained popularity due to its potential beneficial properties.

Despite its popularity, medical-scientific research is still ongoing today, and its legality varies across jurisdictions. As with any substance, it is vital that you carefully consider the potential risks and benefits and consult a medical professional before using products containing this cannabinoid.


And this article on the cannabinoid HHC ends here, hoping to have been of help, see you in the next article!

Greetings from the Annibale Seedshop Team!


Davide V, CEO, Founder & Geneticist